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Vol. 109. Num. 6.July - August 2018
Pages e37-e46Pages 465-576
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Vol. 109. Num. 6.July - August 2018
Pages e37-e46Pages 465-576
Review
DOI: 10.1016/j.adengl.2018.03.018
The Value of Adjuvant Radiotherapy in Cutaneous Squamous Cell Carcinoma: A Review
Utilidad de la radioterapia en adyuvancia en el carcinoma epidermoide cutáneo
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J. Cañuetoa, A. Jakab, A. Tollc,
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atoll@parcdesalutmar.cat

Corresponding author.
a Servicio de Dermatología, Complejo Asistencial Universitario de Salamanca, IBSAL Instituto de Investigación Biomédica de Salamanca, Complejo Asistencial Universitario de Salamanca, Salamanca, España
b Servicio de Dermatología, Hospital Universitari Germans Trias i Pujol, Badalona, España
c Servicio de Dermatología, Hospital del Mar, Parc de Salut Mar, Barcelona, España
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Tables (3)
Table 1. Radiotherapy Modalities for Skin Cancer.
Table 2. Classification of High-Risk Squamous Cell Carcinoma According to European, US, and Australian Guidelines.
Table 3. Indications for Adjuvant Radiotherapy According to European, US, and Australian Guidelines.
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Abstract

Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer in humans and its incidence is rising. Although surgery is the treatment of choice for cSCC, postoperative adjuvant radiotherapy has an important role in local and locorregional disease control. In this review, we analyze the value of postoperative radiotherapy in the management of high-risk cSCC (in particular, cases with perineural invasion), cSCC with positive surgical margins, and locally advanced cSCC (with parotid gland and/or lymph node metastasis).

Keywords:
Cutaneous squamous cell carcinoma
Radiotherapy
Adjuvant
Postoperative
High-risk
Resumen

El carcinoma epidermoide cutáneo (CEC) es el segundo tumor más frecuente en humanos y tiene una incidencia creciente. Aunque la cirugía representa el tratamiento de elección del CEC, la radioterapia adyuvante postoperatoria tiene un papel relevante en el control local y locorregional de la enfermedad. En esta revisión analizamos la utilidad de la radioterapia postoperatoria en el manejo del CEC de alto riesgo (especialmente con infiltración perineural), en el control del CEC con márgenes positivos tras la cirugía y en el CEC localmente avanzado (con metástasis parotídeas o ganglionares).

Palabras clave:
Carcinoma escamoso cutáneo
Radioterapia
Adyuvancia
Postoperatorio
Alto riesgo

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